Med Microbiology & Immunology

The Intersection of Microbial Pathogens & Host Defense

皇冠体育博彩大学医学院的医学微生物学和免疫学系涉及多个研究和教学领域(例如.g., immunology, virology, parasitology, 微生物致病性和流行病学),涉及微生物发病机制和宿主防御之间的交叉. The department is equipped with state-of-the-art facilities, including Illumina MiSeq and Oxford Nanopore technologies, 通常用于涉及微生物全基因组测序的基础科学和临床研究, 使用Becton Dickinson FACSCalibur和独特的Becton Dickinson FACSAria配置进行流式细胞术.

We’re an enthusiastic group of faculty, staff, 博士后和学生在一个鼓励个人和集体通过出版物和演讲取得成就的环境中工作.

Students 

医学微生物学和免疫学专业通常有7到10名研究生.  学生感兴趣的其他信息也会定期发布在X系网站上.

Cost of Study

Financial Aid 

经济援助通常以津贴和/或学费减免的形式提供.

Applying 

完成的申请必须在2月1日或之前提交给研究生院,以便在秋季学期入学. Applications should include transcripts, scores on the General Test of the Graduate Record Examinations, and three letters of recommendation. Written correspondence should be addressed to:

Patrick C. Swanson, PhD
Director of Graduate Studies
Department of Medical Microbiology and Immunology
Creighton University School of Medicine
2500 California Plaza
patrickswanson@xahuachuang.com
402.280.2716

Research Facilities

该部门在现代建筑中占地16000平方英尺. 超过四分之三的可用空间用于研究实验室, which are completely equipped with all essential facilities, including a BSL-3 biocontainment facility. There is also a centrally located departmental pool of major equipment. Ample space is provided for each student. 设备齐全的动物宿舍和动物手术室. 我们的附属临床微生物实验室设备齐全,可以在诊断微生物学方面进行广泛的指导, immunopathology, and viral serology. 健康科学图书馆有21万多册图书,目前收到1600本连载.

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Department News

Grants

  • Dr. Jason Bartz and Dr. Tony Kincaid have received a $2.4400万美元的五年NIH拨款,用于更密切地研究感染性朊病毒蛋白质.
  • Dr. Richard Goering has received a $500,阿联酋-美国国立卫生研究院为研究迪拜的耐甲氧西林金黄色葡萄球菌流行病学提供了3万美元的资助.
  • Dr. Travis Bourret has received a new $1.美国国立卫生研究院拨款800万美元,用于研究导致莱姆病的细菌如何感知环境并对环境做出反应,从而使其能够通过蜱虫传播给人类. 
  • Dr. Qi Yuan has received a new $250,1万美元的美国农业部拨款,用于研究影响朊病毒持续存在和传播的环境因素.g., chronic wasting disease) in natural settings.
  • Dr. Patrick Swanson has received a new $250,000 NIH grant to purchase a Bigfoot Cell Sorter and a $383,000 NIH资助他的免疫库多样化机制的研究. 
  • Dr. Sudhanva Kashyap获得了一项新的40万美元NIH拨款,用于研究寄生虫抗寄生虫药物靶点.

News

  • Streck Laboratories recently named a conference room in honor of Dr. 南希·汉森,以表彰她在开发耐抗生素细菌病原体分子诊断方面的开创性工作.
  • Dr. 帕特里克·斯旺森最近获得了医学院杰出研究事业奖.
  • Dr. Jason Bartz received the 2024 Creighton University Dr. Robert Heaney Graduate Mentor Award.
  • Dr. 理查德·戈林(Richard Goering)就他发表的关于“隐形”MRSA的研究接受了当地电视台的采访.
  • Dr. Jason Bartz最近在美国微生物学会讨论了他在朊蛋白和海绵状脑病方面的工作 “Meet the Microbiologist” podcast.  Dr. Bartz was also recently appointed to the University of Minnesota Chronic Wasting Disease Resource Center as one of 14 international experts.

最近的部门出版物(更详细的信息可以在个别教师页面上找到):

Woerman AL, Bartz JC. Effect of host and strain factors on à-synuclein prion pathogenesis. Trends Neurosci. 2024 May 27:S0166-2236(24)00084-5. doi: 10.1016/j.tins.2024.05.004. Epub ahead of print. PMID: 38806297.

Schwabenlander MD, Bartz JC, Carstensen M, Fameli A, Glaser L, Larsen RJ, Li M, Shoemaker RL, Rowden G, Stone S, Walter WD, Wolf TM, Larsen PA. 朊病毒法医:一种多学科方法来调查非法鹿尸体处理场的CWD. Prion. 2024 Dec;18(1):72-86. doi: 10.1080/19336896.2024.2343298. Epub 2024 Apr 26. PMID: 38676289; PMCID: PMC11057675.

Bartz JC, Benavente R, Caughey B, Christensen S, Herbst A, Hoover EA, Mathiason CK, McKenzie D, Morales R, Schwabenlander MD, Walsh DP, Nc北美跨学科慢性消耗性疾病研究联盟成员. Chronic Wasting Disease: State of the Science. Pathogens. 2024 Feb 2;13(2):138. doi: 10.3390/pathogens13020138. PMID: 38392876; PMCID: PMC10892334.

Nguyen BT, Chapman NM, Johnson N, Stessman HAF, Tracy S, Drescher KM. 闭式环状染色体外元件ofÿNaegleria pringsheimiÿDe Jonckheere(株Singh)的完整序列. Microbiol Resour Announc. 2024 Apr 11;13(4):e0080623. doi: 10.1128/mra.00806-23. Epub 2024 Mar 21. PMID: 38509051; PMCID: PMC11008152.

Nguyen BT, Chapman NM, Johnson N, Stessman HAF, Tracy S, Drescher KM. 闭合环状染色体外元件(CERE)的完整序列ofÿNaegleria australiensisÿDe Jonckheere(菌株PP 397). Microbiol Resour Announc. 2023 Oct 19;12(10):e0032123. doi: 10.1128/MRA.00321-23. Epub 2023 Sep 26. PMID: 37750728; PMCID: PMC10586121.

Gaber Y, TumAllah HM, AbdelAllah NH, Al-Zereini WA, Abu-Lubad MA, Aqel AA, Elkhatib WF, Goering RV, Soliman AM. Al-Karak医院分离的aÿspaÿType t4407 ST6-SCCmecÿType IVa Methicillin-ResistantÿStaphylococcus aureusÿStrain的出现和基因组特征, Jordan. Medicina (Kaunas). 2024 Feb 9;60(2):295. doi: 10.3390/medicina60020295. PMID: 38399582; PMCID: PMC10890080.

Schlatterer K, Napp M, Gleich S, Monecke S, Arnold A, Kiefer-Trendelenburg T, Goering R, Strommenger B, Werner G, Daeschlein G. 2023. 社区相关的耐甲氧西林金黄色葡萄球菌(ca-MRSA)作为一种大流行病原体:危险因素和对医疗保健的影响. Aktuelle Dermatologie 49:68-75.

Scharn CR, Tickler IA, Tenover FC, Goering RV. 影响邻近染色体区域的耐甲氧西林金黄色葡萄球菌SCCmecÿInstability的特征, Including the Gene for Staphylococcal Protein A (spa). Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0237421. doi: 10.1128/aac.02374-21. Epub 2022 Mar 7. PMID: 35254090; PMCID: PMC9017337.

Siedlik JA, Watson CJ, Raine MA, Cheng AV, Goering RV, Stessman HAF, Belshan M. 美国内布拉斯加州严重急性呼吸综合征冠状病毒2型流行病学和基因组分析, March 2020-2021. Front Microbiol. 2022 May 18;13:878342. doi: 10.3389/fmicb.2022.878342. PMID: 35663859; PMCID: PMC9158493.

邓思,何伟,龚毅,李敏,王勇,夏志,张晓涛,黄帕切科AS, Naqib A, Jenkins M, Swanson PC, Drescher KM, Strauss-Soukup JK, Belshan M, Chen XM. 隐孢子虫使用CSpV1激活宿主I型干扰素并减弱抗寄生虫防御. Nat Commun. 2023 Mar 16;14(1):1456. doi: 10.1038/s41467-023-37129-0. PMID: 36928642; PMCID: PMC10020566.

Worth AN, Palmer VL, Schabla NM, Perry GA, Fraser-Philbin AN, Swanson PC. 受体编辑抑制vh12转基因小鼠中磷脂酰胆碱特异性B细胞的发育. Cell Rep. 2022 Jun 14;39(11):110899. doi: 10.1016/j.celrep.2022.110899. PMID: 35705027; PMCID: PMC9716649.

Richards CL, Bontemps-Gallo S, Bourret TJ. Editorial: Host-pathogen interactions: the metabolic crossroads. Front Cell Infect Microbiol. 2023 May 16;13:1212051. doi: 10.3389/fcimb.2023.1212051. PMID: 37260702; PMCID: PMC10227595.

Hamik J, Bourret TJ, Smith H, Herman M, Birn R, Dawdy T, Zuffante MJ, Donahue MA. 内布拉斯加州莱姆病当地传播与伯氏疏螺旋体感染肩胛骨伊蚊(蜱螨:伊蚊科)的检测, USA, 2021. Zoonoses Public Health. 2023 Jun;70(4):361-364. doi: 10.1111/zph.13031. Epub 2023 Feb 13. PMID: 36785942.

Maclean AKW, Morrow S, Niu F, Hanson ND. What Contributes to the MIC? Beyond ?-Lactamase Gene Detection in Klebsiella pneumoniae. J Infect Dis. 2024 Apr 24:jiae204. doi: 10.1093/infdis/jiae204. Epub ahead of print. PMID: 38654105.